EuFert

EUFERT Q10 IS THE food supplement FORMULATED IN ORDER TO ENHANCE MALE FERTILITY
  • Uses

To improve male fertility in case of:

  • low sperm quality (Oligoastenoteratozoospermia)
  • ART protocol
  • varicocele (before and after surgery) stress
  • How to use

EuFert Q10, food supplement formulated in order to enhance male fertility.

One sachet per day.

  • Risk factors

The most common risk factors for male infertility are:

  • varicocele
  • cryptorchidism
  • erectile dysfunction
  • scrotal hyperthermia
  • stress and environmental risks
  • lifestyle (smoking, sedentary life, unhealthy eating, obesity, alcohol and drug abuse)
  • sexually transmitted diseases
  • uro-seminal infections and epididymitis
  • genetic and hormonal causes
  • Active ingredients
This amino acid helps to maintain good sperm motility and enhances energy metabolism of the spermatozoon. Numerous studies have confirmed the benefits of arginine also in treatment of erectile dysfunction, because, thanks to its ability to regulate vasodilation it allows a better erection.
It is a fat-soluble component of the mitochondrial respiratory chain. It acts as powerful Antioxidant. It has also been observed to inhibits the formation of hydroxyperoxide in the seminal fluid and it is correlated with count and motility sperm.
It plays a fundamental role in sperm maturation and in their metabolism, providing for guaranteeing ready-to-use energy. Its concentration is therefore correlated with the motility of the sperm. Its administration has shown the ability to improve concentration and total count sperm in subjects with asthenozoospermia.
Thanks to its marked antioxidant, anti-inflammatory and antibacterial properties it improves the quality of the semen.
This micronutrient is considered fundamental because it acts as a cofactor of glutathione peroxidase and therefore protects the cell from oxidative stress. Its concentration in the seminal fluid is positively correlated to sperm concentration.
Oligodynamic principle involved in many biological processes, including DNA replication and exchange of free radicals, it has antioxidant property too. Zinc deficiency causes a decrease in levels of testosterone, and an increase in serum markers of oxidative stress and an increased apoptosis of spermatogonia, spermatocytes and spermatids. Indeed, zinc semen levels are higher in normospermics than in oligoastenoteratozoospermic patients.
  • Why EuFert?

Male infertility occurs whenever there is an alteration of normal production, maturation, motility and release of spermatozoa (1, 2). The cause of this spermatic alteration is multifactorial, but genetic, organic and environmental factors recognize the oxidative stress as a common factor. Oxidative stress occurs when reactive oxygen species (ROS, Reactive Oxygen Species) overcome the natural antioxidant defenses present in the seminal fluid and within the spermatozoon, causing cellular damage (3, 4): an alteration of the integrity of the spermatic DNA compromises the paternal genomic contribution to the embryo, which has a fundamental importance both in natural conception and in assisted reproduction techniques (ART). EuFert Q10 has a unique and specific formulation, made to provide an adequate supply of micronutrients (vitamins and minerals) able to improve male fertility.

EuFert Q10 contains Arginine (3g), a nitric oxide donor, a powerful vasodilating and antioxidanr agent; Coenzyme Q10 (200 mg) with antioxidant properties and able to improve count and sperm motility; L-Carnitine (300 g), which plays a fundamental role in the maturation of the spermatozoa and in their metabolism, improving their concentration and total count in subjects with asthenozoospermia (5, 6). EuFert Q10 also contains N-Acetylcysteine (600 mg), with antioxidant, anti-inflammatory and antibacterial properties; Selenium (0.04 mg) and Zinc (11.25 mg) which have a protective effect against cellular oxidative stress: their concentration in the fluid seminal is positively correlated to sperm concentration (7, 8, 9, 10). Male infertility requires a multi-modal and articulated therapy to cure all predisposing and precipitating factors. In particular, a healthy lifestyle, based on a varied diet rich in micronutrients, the regular physical exercise, the abstention from recreational toxicants and sexual protection are winning allies to improve male sexual health.

EuFert Q10, thanks to its exclusive formulation, helps to enhance fertility and procreative male capacity, reducing oxidative stress and ensuring a considerable improvement in fertilizing capacity (increased quality, number and motility of spermatozoa in the ejaculate), even in case of assisted reproductive technology.

Fig. 1 The organs that are part of the male reproductive system are located mostly outside the abdomen. The testicles, also called male gonads, have the task of producing sperm, and of secreting testosterone which, in humans, plays an essential role in regulating the development of sexual characteristics and the function of reproduction. Other accessories organs (epididymis, vas deferens, seminal vesicles, prostate, ducts ejaculators, urethra, urethral bulb glands and penis) contribute to produce the remaining components of the sperm, to preserve and nourish the spermatozoa and to transport the sperm inside the reproductive feminine system to achieve conception. A determining factor to carry out all these functions is maintaining a temperature within the scrotum lower than 1°C than the one in the abdomen.
  • Bibliography
  1. Collins JA, Van Steirteghem A. Overall prognosis with current treatment of infertility. Hum Reprod Update 2004; 10:309-316.
  2. Shrif K. Reclassification of azoospermia: the time has come? Hum Reprod 2000; 15: 237-238.
  3. Valko M, Jomova K, Rhodes CJ, et al. Redox- and non-redox-metal-induced formation of free radicals and their role in human disease. Arch Toxicol 2015;90:1-37.
  4. Saleh RA, Agarwal A. Oxidative stress and male infertility: from research bench to clinical practice. J Androl 2002; 23: 737-52.
  5. Salas-Huetos A, Bulló M, Salas-Salvadó J. Dietary patterns, foods and nutrients in male fertility parameters and fecundability: a systematic review of observational studies. Hum Reprod Update 2017;23(4):371-89.
  6. Gaskins AJ, Chavarro JE. Diet and fertility: a review. Am J Obstet Gynecol 2018; 218(4):379-89.
  7. Eroglu M, Sahin S, Durukan B, et al. Blood serum and seminal plasma selenium, total antioxidant capacity and coenzyme q10 levels in relation to semen parameters in men with idiopathic infertility. Biol Trace Elem Res 2014;159:46-51.
  8. Omu AE, Al-Azemi MK, Al-Maghrebi M, et al. Molecular basis for the effects of zinc deficiency on spermatogenesis: an experimental study in the Sprague-dawley rat model. Indian J Urol 2015;31:57-64.
  9. Lanzafame FM, La Vignera S, Vicari E, et al. Oxidative stress and antioxidant medical treatment in male infertility. Reprod Biomed Online 2009; 19: 638-659.
  10. Ross C, Morriss A, Khairy M, et al. A systematic review of the effect of oral antioxidants on male infertility. Reprod Biomed 2010; 20: 711-723.